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J&J Lung Cancer Ambitions Possibly Boosted By New Rybrevant Data

New Rybrevant Data Could Boost J&J Lung Cancer Ambitions

 
• By Joseph Haas

Improvements in PFS compared to chemotherapy may help broaden Rybrevant’s indication in EGFR-mutated non-small cell lunger cancer. Investors await data from a head-to-head trial testing it versus AstraZeneca’s Tagrisso.

Since obtaining US Food and Drug Administration approval of Rybrevant in a small subset of non-small cell lung cancer (NSCLC) patients in 2021, Janssen Pharmaceutical Cos. has eyed a much bigger opportunity by seeking data readouts that would position its bispecific antibody to compete with AstraZeneca PLC’s Tagrisso (osimertinib) in EGFR-driven mutations that comprise a larger segment of the NSCLC population.

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