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Genentech Joins Hunt For ‘Molecular Glue’ Drugs With Orionis

Will Aim At ‘Undruggable’ Oncology and Neurodegeneration Targets

 
• By Andrew McConaghie

Genentech is broadening its stake in the protein degradation field, following BMS and Merck & Co into molecular glue drugs.

Roche_HQ

Genentech is to collaborate with Orionis Biosciences to discover and develop new ‘molecular glue’ medicines, a field which is already attracting much big pharma investment.

The biotech will receive $47m upfront from the Roche subsidiary to leverage its Allo-Glue platform to discover novel small-molecule drugs for challenging targets in major disease areas, including oncology and neurodegeneration

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