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Novartis’s Lutathera To Be First Radiopharmaceutical In Frontline Use After Trial Success

Company Hails ‘Quite Remarkable’ Phase III Results

 
• By Andrew McConaghie

The Swiss pharma giant is building momentum in radiopharmaceuticals by racking up positive pivotal trial data and overcoming manufacturing bottlenecks.    

Novartis

Novartis looks set to gain the first ever radiopharmaceutical approval in a frontline setting after Lutathera achieved success in a Phase III study in pancreatic cancer.

The Swiss pharma giant has reported that the NETTER-2 trial met its primary endpoint of improvement in progression-free survival (PFS) and the key secondary endpoint of objective response rate in patients with Grade 2 and 3 advanced newly diagnosed somatostatin receptor (SSTR)-positive gastroenteropancreatic neuroendocrine tumors (GEP-NETs) after first-line treatment with

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