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Sanofi’s Tzield Delays Children’s Type 1 Diabetes Progression, But Falls Short On Clinical Impact

 
• By Andrew McConaghie

Sanofi paid $2.9bn for Tzield and its developer Provention earlier this year, but a mixed readout in its key Phase III study will raise doubts among analysts about its long-term prospects in later-stage patients.

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Sanofi has high hopes for its anti-CD3 antibody therapy, Tzield, in delaying the progression of type 1 diabetes but despite achieving its primary biomarker goal, its latest Phase III has fallen short on proving a positive impact on patients’ condition.

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