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First Signs Of Efficacy From Biogen’s Tau-Targeting Antisense Drug

 
• By Andrew McConaghie

After showing an impressive 60% reduction in tau levels in the brain, Biogen’s Phase I study of BIIB080 has now demonstrated early signs of an impact on cognition and daily living for Alzheimer’s patients.

Biogen

Earlier this year, Biogen presented eye-catching results from its Alzheimer’s disease candidate BIIB080, which showed it produced ”unprecedented” reductions in the tau protein – and has now followed this with small but encouraging signs that this effect also helps to slow the disease’s progress.

Data from the Phase Ib study presented in March showed 60mg and 115 mg quarterly intrathecal doses of the antisense...

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