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Takeda Will Take TYK2 Inhibitor Into Phase III, Looks For Dosing Edge Over BMS Rival

 
• By Andrew McConaghie

The Japanese pharma company has bet big on its TYK2 inhibitor, but it must demonstrate competitive safety and efficacy if it is to challenge Bristol Myers Squibb’s first-to-market Sotyktu.

Back in December 2022, Takeda paid out a near-record-breaking $4bn upfront to acquire Nimbus Therapeutics' TYK2 inhibitor, TAK-279 in the expectation that it could be an oral therapy blockbuster for conditions such as psoriasis and psoriatic arthritis. (Also see "Takeda Aims At BMS’s Sotyktu In $4bn Deal For Nimbus’s TYK2 Inhibitor" - Scrip, 13 December, 2022.)

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• By Lisa Takagi

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• By Andrew McConaghie, Edwin Elmhirst, and Dexter Jie Yan

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