Gilead’s TIGIT Program Perks Up After Lung Cancer Letdown

Oncology, HIV Offer R&D Catalysts In 2024

The drug maker announced early data for zimberelimab/domvanalimab in gastrointestinal cancers that it called encouraging, though an analyst was more skeptical due to limited interpretability.

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Gilead Sciences, Inc. got what it called encouraging news from its anti-PD-1/TIGIT program just before announcing its third quarter earnings as a Phase II study showed clinical activity for the immuno-oncology combination in upper gastrointestinal cancers. It also highlighted a number of oncology, inflammation and virology catalysts for 2024, including earlier-than-expected data for its long-acting HIV pre-exposure prophylaxis (PrEP) program.

Foster City, CA-based Gilead announced its third quarter earnings on 7 November, with overall revenues of $7.1bn that were flat compared with $7bn in the third quarter of 2022, but...

Key Takeaways
  • Gilead announced early data from a Phase II study of zimberelimab/domvanalimab in upper GI cancers the same day it announced Q3 earnings.

  • The...

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