Gene editing, with which Vertex Pharmaceuticals Incorporated has seen success, is one thing; base editing may be another. Shares in Verve Therapeutics, Inc. cratered on the NASDAQ after data presented at the American Heart Association on 12 November revealed that two patients treated with Verve’s base-editing anti-cholesterol therapy VERVE-101 suffered severe cardiovascular events.
Audience Unimpressed By Verve’s Base Playing
Verve’s shares dropped hard on its recent Phase I data, and it might be up to Lilly to retore investor confidence.

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Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.