The closely watched Phase III clinical trials for Vertex Pharmaceuticals Incorporated’s NaV1.8 inhibitor VX-548 in the treatment of moderate-to-severe acute pain following abdominoplasty, bunionectomy and other procedures or events successfully met most of the three studies’ endpoints. As a result, the company plans to submit the drug for US Food and Drug Administration approval by mid-2024 and, if approved, it could reach the market in time for Medicare reimbursement changes favoring non-opioids.
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