Latigo Raises $135m To Channel Vertex

The start-up is aiming to develop a NaV1.8 inhibitor for pain, but previous efforts here have met with more failure than success.    

Spinal cord nerve energy impulses into brain

A fortnight or so after Vertex Pharmaceuticals Incorporated’s VX-548 achieved one of the vanishingly few breakthroughs by a non-opioid painkiller, a start-up has emerged to develop a similarly acting analgesic. Latigo Biotherapeutics has closed a $135m series A financing aimed at funding a Phase I study of LTG-001, an oral NaV1.8 inhibitor.

Sodium channel blockers, however, have a checkered history

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