Shortly after a Phase III trial failed to confirm Amylyx Pharmaceuticals, Inc.’s Relyvrio benefit in amyotrophic lateral sclerosis (ALS), Seelos Therapeutics, Inc. has revealed that its investigational drug SLS-005 did not meet the primary endpoint in a mid- and late-stage basket study, but showed an efficacy signal in patients who had not taken Relyvrio.
Seelos Aims For Conservative Approach After ALS Drug Shows Efficacy Signal
CEO Raj Mehta told Scrip Seelos anticipates conducting a Phase III study of SLS-005 after the cohort in HEALEY ALS failed overall, but indicated some efficacy in patients not receiving Relyvrio.
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