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AstraZeneca And Daiichi Get Low

 
• By Elizabeth Cairns

A hit with Enhertu in an earlier setting in HER2-low breast cancer patients, and in ultralow expressers, heightens expectations.    

Meter with low reading
• Source: Shutterstock

The long-awaited topline success of Daiichi Sankyo Co., Ltd. and AstraZeneca PLC’s DESTINY-Breast06 trial of their antibody-drug conjugate Enhertu is significant twice over. Firstly it could allow the product to move ahead of chemotherapy in breast cancer patients with high or low expression of HER2, for whom it is already largely established as standard-of-care post-chemo.

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