1. Scrip
  2. >>Business

Development Versus Dealmaking: How To Obtain A Blockbuster

 
• By Elizabeth Cairns

Most of the companies with blockbuster drugs approved over the past decade oversaw their clinical development internally. Lilly holds the lead with eight blockbusters developed in-house.  

Discovery Versus Dealmaking
• Source: Shutterstock

Considering that an actual or potential blockbuster developed by a smaller biotech is catnip to big pharma, obtaining a blockbuster by buying it might be expected to be the most common strategy. But according to data from Evaluate Pharma, only 81 companies with blockbusters gained them through dealmaking – at least when the parameters are limited to clinical stages.

Meanwhile, 105 drug companies either discovered blockbusters internally or bought them before clinical trials had started. Many companies that developed...

More from Business

More from Scrip

Executives On The Move: Legend Biotech Gets New CFO From AstraZeneca

Recent moves in the industry include an ex-Pfizer exec as the new CEO at Cha Vaccine Institute and a C-suite shuffle at Paragon Therapeutics, plus six other companies get new CFOs.

DualityBio Eyes 1L Use For ADC Combos With BioNTech’s Bispecific

 
• By Dexter Jie Yan

Duality is fast-tracking the development of three of its ADC candidates in combination with partner BioNTech's BNT327, an anti-PD-L1/VEGF-A bispecific antibody, in four studies, with certain cohorts evaluating first-line use in various cancers.

Lilly’s Verzenio Scores First OS Improvement In Key Breast Cancer Setting In Decades

 
• By Alaric DeArment

The drugmaker announced topline results for the CDK4/6 inhibitor in early HR-positive, HER2-negative breast cancer, giving it a competitive edge over Novartis’s Kisqali.