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EASL: Tirzepatide Is The One To Beat In MASH

 
• By Elizabeth Cairns

An important mid-stage trial succeeds, but an odd finding on the fibrosis endpoint will spur close examination of Lilly’s incretin.    

Winners
• Source: Alamy

Tirzepatide has already proven itself highly effective in diabetes and obesity; now it is starting to look like the best bet in metabolic dysfunction-associated steatohepatitis (MASH), too. Improvements in both MASH and liver fibrosis after a year’s treatment with Eli Lilly and Company’s GIP/GLP-1 agonist look competitive with the best MASH therapies on a cross-trial basis.

Key Takeaways
  • Phase II data coming at EASL position Lilly’s tirzepatide ahead of most other MASH therapies.

Data from the keenly awaited SYNERGY-NASH trial are to be presented at the European Association for the Study of the...

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