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Vir Hopes To Take On Gilead’s Hepcludex After Positive Early Hepatitis D Results

 
• By Alaric DeArment

The biotech presented preliminary data on chronic hepatitis D from the Phase II SOLSTICE study of tobevibart and elebsiran at the EASL meeting.

• Source: Shutterstock

Vir Biotechnology, Inc. is planning to test its monoclonal antibody tobevibart, combined with the Alnylam Pharmaceuticals Inc.-partnered elebsiran, head-to-head against Gilead Sciences, Inc.’s Hepcludex (bulevirtide) in chronic hepatitis D, executives told analysts following the presentation of Phase II data for the combination at the European Association for the Study of the Liver (EASL) annual meeting.

Vir presented preliminary data on 5 June from the Phase II SOLSTICE study, showing a high virologic response and liver enzyme normalization in people living with hepatitis D after 12 and 24 weeks

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