Gilead Sciences, Inc. reported data from the first of two pivotal studies of twice-annual dosing of its capsid inhibitor lenacapavir for HIV pre-exposure prophylaxis (PrEP) on 20 June, showing zero infections in cisgender women and establishing superiority against background incidence of infection and a control group that received Gilead’s daily oral combination therapy Truvada (emtricitabine/tenofovir disoproxil) for PrEP.
Gilead’s Twice-Annual Sunlenca Posts Zero Infection Rate In PrEP Trial
Lenacapavir is halfway to the pivotal data needed to file for twice-annual administration in PrEP, after demonstrating superiority against both background incidence of HIV infections and Truvada.
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