Two San Francisco Bay-area biotechs – Adverum Biotechnologies, Inc. and 4D Molecular Therapeutics Inc. – presented updated Phase II readouts on 17 July for their gene therapy candidates for wet age-related macular degeneration (AMD), with each company saying it plans to move its candidate into Phase III during 2025.
Adverum, 4D Molecular Present Dueling Phase II Datasets In Wet AMD
The two biotechs each hope to offer an Eylea-sparing regimen to wet age-related macular degeneration patients with gene therapies that induce natural production of aflibercept.

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