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BioNTech and MediLink’s HER3 ADC Back In The Game After Safety Concerns

 
• By Andrew McConaghie

The partners still believe their HER3-targeting ADC can rival Merck & Co and Daiichi Sankyo’s frontrunner, even at a new lower dose range.

Mainz, Rheinland-Pfalz, Germany-9. September 2020 Biontech building in Mainz with the sun shining and waving flags
• Source: Florian Imbusch / Shutterstock.com

BioNTech and MediLink Therapeutics will resume enrolment in a Phase I study of their antibody-drug conjugate, BNT326, in lung and breast cancer patients after a partial hold related to treatment-related deaths was lifted.

BNT326/YL202 is a human epidermal growth factor receptor 3 (HER3)-targeting antibody-drug conjugate (ADC) candidate, a field as yet with no...

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