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Recursion’s REC-994 Passes Phase II, But Needs To Find Right Dosage, Endpoints For Next Study

 
• By Alaric DeArment

The study, in cerebral cavernous malformation (CCM), hit the safety primary endpoint and showed signals in efficacy, but analysts pointed out that the bar for success in the disease remains unclear.

• Source: Shutterstock

Results from Recursion Pharmaceuticals, Inc.’s Phase II SYCAMORE study of REC-994 in symptomatic cerebral cavernous malformation (CCM) drew uncertainty despite meeting the trial’s safety and tolerability primary endpoint, as the study showed signals of efficacy, but in a disease where there is a lack of clarity on what constitutes success.

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