Depemokimab’s Secondary Stumbles In Asthma

GSK’s ultra-long-acting biologic cuts asthma attacks, but misses on all the secondary endpoints in the twin SWIFT trials could limit its appeal.    

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• Source: GSK

What price convenience? That is the question raised by the full data from the twin pivotal studies of GSK plc’s asthma candidate, depemokimab. The anti-IL-5 antibody reduced asthma attacks by a similar degree to a handful of marketed asthma biologics, but it is injected just twice a year, whereas most of its rivals are monthly jabs.

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