Metsera Enters Race With Potential Monthly GLP-1 Injection For Obesity

Five months after its debut, the company plans to take its candidate, MET-097, into Phase IIb development.

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Metsera, Inc. is stepping into the rapidly growing ring of companies developing GLP-1 agonists for obesity with new Phase I data showing significant weight reduction as well as the potential for monthly dosing of its candidate, MET-097.

Privately held, New York-based biotech Metsera announced topline results on 24 September for MET-097, a long-acting injectable, fully biased GLP-1 receptor agonist, reporting that it achieved significant and durable weight loss

Key Takeaways
  • Metsera unveiled positive Phase I topline results for its injectable GLP-1 agonist, MET-097, showing 7.5% weight reduction after a month.

  • Results showing further reduction after 51 days indicate the potential for the drug to be dosed once monthly

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