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REGENCY Dandy for Roche In Lupus Nephritis

 
• By Elizabeth Cairns

Gazyva could add the autoimmune condition to its label following a Phase III hit, but it might struggle to differentiate itself from Benlysta and Lupkynis.    

Blue and purple graphic image of pair of kidneys
• Source: Shutterstock

Roche Holding AG could be third to market in the autoimmune disease lupus nephritis after claiming a topline hit in the pivotal REGENCY trial. More people responded to the anti-CD20 antibody in the Phase III study than responded to placebo, and Roche intends to get the drug on the market in this new use “as soon as possible”.

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