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J&J/Legend’s Carvykti Further Cements Myeloma Lead With OS Benefit

 
• By Alaric DeArment

New data from CARTITUDE-4 show a survival benefit in patients with lenalidomide-refractory patients as early as the second line, along with Carvykti being studied for frontline use.

• Source: Shutterstock

Johnson & Johnson and Legend Biotech Corp. look set to further strengthen the commercial positioning of Carvykti (ciltacabtagene autoleucel) as the BCMA-directed CAR-T cell therapy for multiple myeloma becomes the first to show an overall survival (OS) benefit in a key population.

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