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Henlius And Outlook Move Forward With Ophthalmic Bevacizumab

Positive Results For Henlius’ Essex-Partnered HLX04-O, As Outlook Re-Submits In US

 
• By Dave Wallace

Henlius has reported progress in its development of a bevacizumab product for treating ophthalmic diseases, with its Essex-partnered HLX04-O candidate meeting its primary endpoint in a Phase III trial. Meanwhile, Outlook Therapeutics has taken another shot at getting its own ophthalmic bevacizumab approved in the US after resubmitting its filing.

Two firms are moving ahead with ophthalmic bevacizumab products (Shutterstock)

Shanghai Henlius Biotech has celebrated positive results for its HLX04-O candidate, after the proposed bevacizumab product for treating ophthalmic diseases met its primary endpoint in a Phase III trial.

Since 2020, Henlius has partnered with fellow Chinese firm Essex Bio-Technology on development of the product, ticking off multiple milestones for the project over the intervening years. These have included dosing its first patient in a Phase I trial back in 2021, before kicking off a Phase III study

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