October Surprise: How Amgen’s Aflibercept Launch Shook Up US Biosimilars In 2024

As US Market Approaches Tenth Anniversary Of First Biosimilars Approval And Launch

As the US biosimilars market approaches the end of its first decade, it has seen another busy year, with Amgen’s surprise launch of a rival to Eylea shaking up expectations as other first-time approvals rolled in throughout 2024.

Amgen’s ophthalmic launch surprised the market in 2024 (Shutterstock)

In March 2025, the US biosimilars market will celebrate ten years since the first biosimilar received approval from the US Food and Drug Administration, under the Biologics Price Competition and Innovation Act framework that was first introduced back in 2010.

Sandoz’s Zarxio (filgrastim-sndz) – approved in March 2015 and launched later that year – was the forerunner for all of the biosimilar approvals that followed, with the current total number...

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