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In Brief: BriaCell’s Breast Cancer Cell Therapy Boosts Survival In Phase II

 
• By Sushmita Panda

BriaCell announced its cell therapy Bria-IMT plus checkpoint inhibitors bested Gilead’s Trodelvy in a Phase II trial in HR+ breast cancer; a Phase III trial is enrolling.

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Demonstration of a survival advantage for BriaCell Therapeutics Corp.’s Bria-IMT plus checkpoint inhibitors (CPI) over Gilead’s antibody-drug conjugate (ADC) Trodelvy (sacituzumab govitecan) in hormone receptor-positive (HR+) metastatic breast cancer is an encouraging sign as the biotech moves into Phase III.

BriaCell’s Bria-IMT is an off-the-shelf targeted cell-based immunotherapy, a genetically engineered whole-cell vaccine that is thought to indirectly attack cancer cells by producing breast cancer antigens that are recognized by...

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