Bristol’s Opdivo + Yervoy Gets FDA Liver, Colorectal Cancer Nods

Bristol Myers Squibb notched two approvals in one week for its immuno-oncology combination, pitting the regimen head-to-head with Keytruda in a subset of CRC and with two combos in HCC.

Gold "FDA approved" label
BMS's Opdivo + Yervoy combo picks up two more US indications (Shutterstock)

Bristol Myers Squibb obtained two US Food and Drug Administration approvals during the week of 7 April for combination therapy with its immuno-oncology stalwarts Opdivo (nivolumab) and Yervoy (ipilimumab) in liver and colorectal cancer settings, which should help the biopharma vie against strong competition in the IO space.

Key Takeaways
  • Bristol’s Opdivo + Yervoy combo obtains FDA okays for colorectal and liver cancer settings.
  • Each approval converted a prior accelerated approval for the combo in second-line treatment to a full approval in the first line

The new approvals brought the combination regimen’s list of indications to nine, according to BMS

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