Gilead Shines Some Light On Its Inflammation Ambitions

Part Of Ongoing Diversification Strategy

CEO Daniel O’Day and EVP-research Flavius Martin highlighted Gilead’s inflammation R&D and dealmaking focus at the recent J.P. Morgan meeting.

Gilead announced a new deal and reworked an old deal in inflammation already this year (Shutterstock)

Gilead Sciences has worked for decades to build a dominant presence in HIV treatment and prevention, but the company is only years into its buildout of an oncology portfolio, with even more work to do to create a comparable pipeline in inflammation. CEO Daniel O’Day and other executives shed some light on the plans to expand in inflammation during the J.P. Morgan Healthcare Conference, just days after buying inflammation assets from LEO Pharma.

Key Takeaways
  • Gilead is diversifying its portfolio over the long term, with inflammation as an important but earlier-stage area of growth, through both internal R&D and external business development.
  • The company’s recent deal to acquire LEO Pharma’s STAT6 program and the $4.3bn CymaBay buy last year added a preclinical opportunity and a commercial asset in inflammation

On 12 January, Gilead announced it will pay $250m up front for LEO’s preclinical oral small molecule STAT6 inhibitors, which may have potential in atopic dermatitis, asthma and chronic obstructive pulmonary disease (COPD), among other indications. O’Day told reporters during a media briefing on the sidelines of the J.P

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