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ASH: Pfizer Sees CD70-Targeted MDS Drug As Better For Frailer Patients

 
• By Alaric DeArment

The drug maker presented Phase I data for PF-08046040 at ASH, having designed it to avoid some of the toxicities associated with antibody-drug conjugates.

(Alaric DeArment/Scrip)

An increasingly popular antigen in hematology-oncology as well as solid tumor oncology is CD70, with a number of players developing therapies to target it. But Pfizer believes its PF-08046040, acquired through its purchase of Seagen, could target CD70 in a way more amenable to elderly patients.

The drug maker presented Phase I data in a poster on 7 December at the American Society of Hematology annual...

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