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AstraZeneca Oral PCSK9 Prospects Pumped After Phase IIb Win

 
• By Kevin Grogan

The UK giant is forecasting peak sales of $5bn plus

AstraZeneca

AstraZeneca may be behind Merck & Co in the race to bring the oral first PCSK9 inhibitor to market but successful mid-stage data for AZD0780 suggest that the UK major could have another cardiovascular blockbuster on its books.

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AstraZeneca Oral PCSK9 Prospects Pumped After Phase IIb Win

 
• By Kevin Grogan

The UK giant is forecasting peak sales of $5bn plus

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• By Kevin Grogan

The biotech has rejected a takeover bid from Nordic Capital but a sale to private equity could be a solution to the public market's continued reluctance to adequately value PureTech’s hub-and-spoke business model.

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The company plans a tiered sales approach as it targets endocrinologists for hypothalamic obesity, which is more widely diagnosed than its current indication for Bardet-Biedl syndrome.