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2025’s Biggest New Launches

 
• By Andrew McConaghie and Edwin Elmhirst

Big pharma once again fails to dominate the top 20 expected best sellers from products due for launch this year. Small-to-medium pharma account for nearly half the list, while Vertex has two products in the top five.

(Shutterstock)

Not even two months into the new year and some of the expected biggest-earning new drugs of 2025 have already been approved.

An updated analysis conducted by Scrip and Evaluate Pharma of drugs expected to be launched this year and their respective 2030 consensus forecast sales shows Vertex’s next -generation cystic fibrosis drug, Alyftrek (vanzacaftor/tezacaftor/deutivacaftor),

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