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10 Clinical Trials To Look Out For In 2025

 
• By Alexandra Shimmings

Scrip surveys some of the more interesting Phase III clinical trial readouts expected this year.

Clinical Trial
An EMA paper discusses specific characteristics of single-arm trials (Shutterstock)

In 2025, the first Phase III clinical readout for a PROTAC degrader is expected in an important milestone for the targeted protein degradation (TPD) field.

The VERITAC-2 study is comparing the orally-bioavailable, small-molecule estrogen receptor PROTAC protein degrader vepdegestrant, which targets the estrogen receptor, against the older injectable selective estrogen receptor

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