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AbbVie Logs Another Phase III Success With Tavapadon In Parkinson’s

 
• By Joseph Haas

The firm said it will file the D1/D5 dopamine receptor agonist for US FDA approval in 2025. The drug may salvage value from AbbVie’s Cerevel buyout.

AbbVie has a third successful Phase III trial for tavapadon (Shutterstock)

Whereas the primary driver of AbbVie’s $8.7bn acquisition of Cerevel, the schizophrenia candidate emraclidine, has been a disappointment, the pharma racked up a third positive Phase III readout for the first-in-class Parkinson’s disease candidate tavapadon on 9 December. Now, AbbVie says it intends to file tavapadon for US Food and Drug Administration approval in 2025.

Key Takeaways
  • AbbVie found success in a third Phase III trial of Parkinson’s disease candidate tavapadon and is planning an FDA filing in 2025.

In the 304-patient, flexible-dose TEMPO-2 study of tavapadon monotherapy – a first- and only-in-class partial agonist of the D1/D5 dopamine...

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