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Corcept’s Relacorilant Shows Benefit In Ovarian Cancer, Expanding Pipeline Opportunity

 
• By Jessica Merrill

A Phase III trial testing the cortisol modulator showed a benefit on PFS and OS in patients with platinum-resistant ovarian cancer.

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Key Takeaways
  • Relacorilant showed a PFS and OS benefit in a Phase III trial in platinum-resistant ovarian cancer. The trial will support regulatory filings in the US and Europe.
  • The company’s stock price nearly doubled as investors were enthusiastic about the data results.
  • Corcept is developing next-generation cortisol modulators that could offer utility across a broad range of tumor types, the firm said.

Corcept Therapeutics’ cortisol modulator relacorilant improved progression-free survival (PFS) and overall survival (OS) in a Phase III trial in patients with platinum-resistant ovarian cancer, paving the way for potential expansion...

The Phase III ROSELLA trial data, unveiled on 31 March, represents the first time relacorilant has shown a Phase III benefit in a cancer indication, with Corcept saying the results...

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