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Gastric Cancer Is Another Perioperative Win For AstraZeneca’s Imfinzi

 
• By Andrew McConaghie

The MATTERHORN study could set Imfinzi up for another new perioperative use, even though the gastric cancer trial has yet to demonstrate an overall survival benefit.

AstraZeneca
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AstraZeneca has recorded another Phase III success in extending the use of its cancer immunotherapy Imfinzi into perioperative settings, this time in for patients with gastric and gastroesophageal junction (GEJ) cancers.

Positive high-level results from the MATTERHORN Phase III trial of perioperative treatment with Imfinzi (durvalumab) in combination with standard-of-care FLOT (fluorouracil, leucovorin, oxaliplatin,

Key Takeaways
  • MATTERHORN is the first Phase III immunotherapy combination trial to show benefits over standard of care in this setting

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