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Immutep’s LAG-3 Adds To Keytruda In First-Line Lung Cancer

 
• By Elizabeth Cairns

Dosing eftilagimod alpha on top of Merck & Co’s blockbuster appears to improve survival, though more robust data are needed.

Paper lungs with a hole on one side, depicting lung cancer, on blue background

Immutep’s eftilagimod alpha has not so much beaten Keytruda as joined it. An investigator-initiated study has shown that addition of the LAG-3 immunotherapy to the standard-of-care first-line non-small cell lung cancer regimen of Merck & Co’s checkpoint inhibitor plus chemo improved survival by around 10 months.

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