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Merck’s Winrevair Slashes Morbidity-Mortality Risk For PAH Patients

 
• By Andrew McConaghie

The ZENITH study is a landmark for Merck’s first-in-class activin signalling inhibitor and pulmonary arterial hypertension treatment.

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Merck & Co’s Winrevair has cut by 76% the risk of death and disease progression in the sickest pulmonary arterial hypertension (PAH) patients in a Phase III study.

The data build the evidence base for the drug, which was first approved in March 2024, and will help

Key Takeaways
  • Once filed and approved, the data would allow Winrevair treatment to expand to patients with the most advanced stage of pulmonary arterial hypertension

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