Potential competitors to Amgen’s Tepezza (teprotumumab), the only approved drug therapy for thyroid eye disease (TED), keep lining up as privately held Sling Therapeutics unveiled positive Phase IIb/III on 14 January data for linsitinib, an oral insulin-like growth factor-1 receptor (IGF-1R) inhibitor that could provide a convenience advantage in a space where the standard of care and several developmental competitors are injectable.
Sling Brings Potential Oral Competition To Amgen’s Tepezza In TED
With positive Phase IIb/III data for IGF-1r inhibitor linsitinib, privately held Sling plans to move into Phase III and compete in thyroid eye disease on convenience and safety.

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