UCB’s Parkinson’s Drug Stalls As Curtain Comes Down On ORCHESTRA

Almost three years to the day, Novartis and UCB heralded a pact that could have been worth $1.5bn to the Brussels-based group for a first-in-class, small-molecule, alpha-synuclein misfolding inhibitor for Parkinson’s disease. However, after a Phase IIa fail, the development of minzasolmin has been terminated.

UCB
• Source: UCB

The Parkinson’s field is littered with clinical failures and another candidate, UCB’s minzasolmin, is the latest to fall in the quest for a disease modifying treatment.

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