Vertex’s Suzetrigine Disappoints In Phase II Pain Study, But Phase III Planning Under Way

Acute Pain Approval Decision Due 30 January

The NaV1.8 inhibitor showed a statistically significant change from baseline in lumbosacral radiculopathy pain, but it was the same as the reduction in the study’s placebo arm.

Lumbosacral radiculopathy is key to a larger peripheral neuropathic pain indication (Shutterstock)

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