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Lilly’s Muscle Builder Looks Strong In GLP-1 Obesity Combo

 
• By Andrew McConaghie

Bimagrumab added to Wegovy increased weight loss and preserved muscle mass, but analysts want to see more safety and efficacy results from a combination with Zepbound.

Studies show that up to 40% of weight loss in GLP-1 use is from muscle, which new therapies aim to counteract.

Eli Lilly’s muscle building drug candidate, bimagrumab, has exceeded expectations in a Phase IIb study, but analysts want to know more about its planned path to approval before getting too excited.

The results show that bimagrumab when combined with Novo Nordisk’s Wegovy (semaglutide) helped increase weight loss in obese adults compared...

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