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Merck & Co./Daiichi Pull Patritumab Deruxtecan BLA On Disappointing OS

 
• By Jessica Merrill

Patritumab deruxtecan is the lead antibody drug conjugate in a $22bn deal signed between the two partners, with the decision marking a disappointing setback

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Key Takeaways
  • Disappointing overall survival data led Merck and Daiichi Sankyo to pull an FDA application for the ADC patritumab deruxtecan in NSCLC.

Merck & Co. and Daiichi Sankyo had hoped the HER3-targeting antibody drug conjugate (ADC) patritumab deruxtecan would be the first...

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