StartUps and SMEs

Kanaph, IMbiologics Shine In Otherwise Idle Q1 Korea IPO Market

Kanaph Therapeutics and IMbiologics launched successful offerings in the IPO-scarce Korean market in the first quarter, as investors become more selective in their targets.

Podcast: Onchilles Pharma’s Neutrophil-Derived Path To Pan-Cancer Therapy

San Diego-based Onchilles Pharma's neutrophil-derived ELANE pathway agent N17350 targets a universal cancer vulnerability, combining direct tumor killing with immune activation. It is now entering first-in-human trials across solid tumors.

At The Immune Frontier, The Hardest Questions Are Commercial

As immune-system science attracts record capital and scientific talent, five companies at the vanguard of the field reveal a shared conviction: the immunome is the organizing principle of human health. The harder question is how to build a business around it.

Excited About AI, Skeptical Of The Price Tag: Seed Investors Sound Off

Seed investors are enthusiastic about AI in drug discovery but skeptical of the valuations it is used to justify. At a recent panel, they drew a sharp line between real capability and an “AI veneer.”

Biotech Britain Vs. The World

Industry leaders share how Britain can strengthen its biotech ecosystem, from capital and regulation to talent and ambition, and what the sector could look like by 2030.

QurAlis In Fundraising Mode After Potentially Value-Creating Readout In ALS

The company’s next VC round hinged on Phase I results for QRL-201, an antisense oligonucleotide designed to restore STMN2 expression in ALS patients, and topline data are promising.

NextGate On Korean Biopharma’s Value Proposition For Investors

NextGate Partners’ managing partner shares his views on the biopharma investment and dealmaking environment in South Korea, along with the particular strengths of companies in the country and R&D areas of focus for this year.

Podcast: Preventing Lung Disease In Preterm Babies

Airway Therapeutics' surfactant protein D replacement therapy showed promising Phase Ib results in preventing bronchopulmonary dysplasia, now advancing to Phase II/III registration trial in preterm infants.

Finance Watch: Santé Ventures Closes $330m Fund, While Gimv Ends Life Science Investments

Private Company Edition: Santé raised a new $330m life science and health care-focused VC fund, while Gimv said it will not back any new life science opportunities. Also, Angitia raised a $130m series D round, QuantX closes a $35m series B and other financings.

From CF To Big Pulmonary Markets: SpliSense’s Strategy To Make Inhaled RNA Work

SpliSense is the first company to show inhaled antisense oligos improve lung function in cystic fibrosis, validating its platform for larger COPD and asthma markets.

Podcast: How Senti Bio’s Programmable Cell Therapy Tackles AML’s Toxicity Problem

Senti Bio CEO Tim Lu explains how logic-gated CAR-NK therapy SENTI-202 distinguishes cancer from healthy cells in AML, achieving 50% response rates with favorable safety.

Beyond Viagra: How Dicot’s Novel Mechanism Could Reshape The $5bn ED Market

The Swedish biotech's LIB-01 offers eight-week efficacy from three-day dosing, targeting high discontinuation rates with current PDE5 inhibitors.