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How Big Pharma is Tackling the R&D Problem

All Big Pharma agree that the R&D crisis exists, but their approaches to dealing with it vary.

"R&D productivity is declining, don't let anyone tell you otherwise," declared Robert Ruffolo, PhD, president of R&D at Wyeth 's pharmaceuticals division, during this year's Pharmaceutical Strategic Alliances conference. All Big Pharma agree that the R&D crisis exists, but their approaches to dealing with it vary.

For Wyeth, it's a numbers game; Novartis AG is talking about an entirely new drug discovery grammar.

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