The blockbuster pharmaceutical era may be a thing of the past and market success for health care products may be harder to achieve, but there is no shortage of ideas, be they from scientists, clinicians, or entrepreneurs. Selecting the right ones to develop is where the skill lies, however, given the high failure rate of products that do make it through development.
Crushingly high, in some cases, especially for “holy grail” targets like Alzheimer’s disease therapy, where the failure rate for drug development is 99.6% for the decade 2002–2012. That was one...
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