Roche Signs Up Ipsen--Again

Roche's October 2003 in-licensing of Ipsen's Phase I GLP-1 analog buys the Swiss group an initial stake in the fast-growing diabetes market. Most established diabetes players already have a compound in this class, but the partners hope that Ipsen's expertise in peptide delivery will set this program apart from competitors'. As the second licensing agreement between Roche and Ipsen in less than a year, the deal further validates Ipsen's pipeline, and suggests that Roche's carefully-managed partnership strategy continues to encourage repeat business.

Compounds related to the natural hormone glucagon-like peptide-1 (GLP-1) have become a hot new class of diabetes drug. GLP-1 is responsible for reducing blood sugar levels when they are too high, and its effects delay the need to move onto insulin injections.

All the major insulin players are aggressively pursuing this target. Eli Lilly & Co. outbid a number of drug...

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