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Fractional Flow Reserve Proves Itself Early In St. Jude’s FAME II Study

St. Jude Medical’s fractional flow reserve technology gave stenting a significant enough edge in stable coronary disease patients that a monitoring board recommended stopping the study early because it would be unethical to continue to randomize patients to the optimal medical therapy control group.

St. Jude Medical’s fractional flow reserve technology for assessing coronary artery lesions hit early success in the large FAME II study, a clear positive for the firm’s PressureWire devices and a potential catalyst for growth in stent procedures.

The trial’s data safety and monitoring board recommended stopping the study early based on the positive results of an interim analysis. The board found a highly statistically significant reduction in...

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