Symplicity Makes Life Difficult For Renal Denervation Programs

A big slice of the device industry, from large-cap firms to venture capitalists, is trying to understand the new reality in the wake of Medtronic’s announcement that its Symplicity hypertension trial missed its endpoint

Medtronic PLC’sbombshell news – the disappointing clinical results for its Simplicity renal denervation product – left a smoking crater on the medtech landscape during last week’s J.P. Morgan Healthcare Conference in San Francisco. Large-cap executives and venture capitalists who saw great promise in the new therapeutic approach spent time trying to gauge the size and scope of the damage on the medtech industry and their own particular portfolios.

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