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Claret Targets TAVR Stroke Risk With Sentinel Embolic Filter Device

The company launched the SENTINEL trial in the U.S., the first prospective, randomized, controlled, blinded trial in the U.S. of a cerebral protection device for transcatheter aortic valve replacement.

Claret Medical Inc. hopes to take advantage of growing awareness among surgeons and interventional cardiologists of the neurological risks associated with transcatheter aortic valve replacement with its Sentinel cerebral protection device designed specifically for TAVR.

“[TAVR] expansion has happened very rapidly, but it's also generated a number of complications that have created new clinical needs,” Claret CEO Azin Parhizgar said in an interview with “The...

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