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NuVasive Inc.

Nuvasive Inc. is developing a platform for minimally invasive spine surgery that combines stereotactic guidance with a neural monitoring system. With neural monitoring, surgeons can access the spine laterally, as opposed to from the back, which entails cutting through bone and splitting muscles. In this way, Nuvasive is advancing medical practice beyond merely replacing the open surgical view with endoscopic access, but otherwise leaving the fusion procedure unchanged.

San Diego, CA, orthopedic surgeon James Marino had witnessed the benefits of orthoscopic triangulation (endoscopic imaging) in his sports medicine practice, and three years ago he approached the venture capital firms Enterprise Partners and Kleiner, Perkins, Caufield & Byers with the notion of applying it to spine surgery. While the idea of using endoscopy on its own wasn't especially innovative, as it turned out, combining it with neural surveillance and instruments for minimally invasive surgery (MIS) of the spine was. The VCs offered Marino up to $4.5 million to validate the concept and begin putting together a company, and NuVasive Inc. was born.

MIS has long been criticized as a technology searching for an application, but NuVasive believes its platform of stereotactic guidance...

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